Dr. Soliman’s academic agenda is centered on optimal nutrition as an integral part of global health promotion and disease prevention; and the public health and social burdens of malnutrition. This umbrella of malnutrition encompasses both overnutrition (obesity and metabolic–related diseases), and undernutrition (macronutrient and micronutrient deficiencies, and eating disorders).
Dr. Soliman’s translational research is focused on obesity, and related metabolic disorders, as well as the impact of micronutrient deficiencies among individuals, across populations, and globally. To promote optimal health, the comprehensive weight management collaborative research program emphasizes nutritious well-balanced diet, physical activity, and behavioral modification to achieve and sustain weight loss and weight maintenance.
Dr. Soliman’s basic laboratory based research focuses on a nutrient-sensing protein termed the mammalian Target of Rapamycin (mTOR), as a master regulator of metabolism, cell growth, and proliferation. Deregulation of the mTOR signaling pathway has been implicated in the pathogenesis of several chronic diseases including insulin resistance, diabetes, metabolic syndrome, and cancer development and progression.
