His research interests include healthcare operations, data analytics, economic decision analysis, and system modeling in healthcare service. His work has examined practice variance and systems analysis for quality and process improvement and new clinical guidelines establishment. Also, his research has focused on economic analysis on industry networks, resource allocations, and R&D process in healthcare service. His research primarily utilizes large datasets and clinical observations derived from both various healthcare database and field study in clinical facilities. He has collaborated actively with hospitals, healthcare research institutes and healthcare delivery organizations both in the U.S. and in foreign countries.