Dr. Karagiannopoulos professional scholarship consists of direct engagement in research and professional service at various levels. His research contributions include publications in the Journal of Orthopaedic and Sports Physical Therapy, Journal of Athletic Training and Journal of Hand Therapy with emphasis on psychometric properties of wrist joint physical impairment assessments and sensorimotor control deficit following distal radius fractures. He has developed an evolving research line on wrist joint sensorimotor control impairment, which is currently linked to his current and prospective student research projects. As a recognition to his clinical research line and recently published research work, Dr. Karagiannopoulos was invited to be the lead author towards the development of the APTA Clinical Practice Guidelines for distal radius fracture rehabilitation. He has also received the American Society of Hand Therapists annual conference best scientific paper in 2013.